THERMOSTABILITY OF LYTIC HETEROPHILE ANTIBODIES FROM HUMAN SERA INFECTED WITH Schistosoma mansoni AND GEO-HELMINTHS. AN IMMUNO-METRIC STATISTICAL ANALYSIS

نویسنده

  • Gregorio S. ATUNCAR
چکیده

(1) Departamento de Bioquímica-Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Antonio Carlos 6627, 30270-901 Belo Horizonte, MG, Brasil. (2) Departamento de Estatística, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil. (3) Centro de Pesquisas René Rachou-Fiocruz, Av. Augusto de Lima 1715, 30190-002 Belo Horizonte, MG, Brasil. (4) Santa Casa de Misericórdia de Belo Horizonte, Belo Horizonte, MG, Brasil Correspondence to: Prof. Paulo Marcos Zech Coelho, Laboratório de Esquistossomose, Centro de Pesquisas René Rachou/Fiocruz, Av. Augusto de Lima 1715, 30190-002 Belo Horizonte, MG, Brasil. E-mail: [email protected] THERMOSTABILITY OF LYTIC HETEROPHILE ANTIBODIES FROM HUMAN SERA INFECTED WITH Schistosoma mansoni AND GEO-HELMINTHS. AN IMMUNO-METRIC STATISTICAL ANALYSIS

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Thermostability of heterophile antibodies from human sera infected with Schistosoma mansoni and geo-helminths. An immuno-metric statistical analysis.

Antibody in human sera that induces lysis of sheep erythrocytes in hemolytic assay was investigated. The present study showed that the presence in serum of the thermostable cytolytic anti-sheep red blood cells antibodies is dependent on the Schistosoma mansoni infection, and this is more frequent in adults than in children. The thermostable characteristic of hemolysins in normal sera was not de...

متن کامل

Schistosoma mansoni-infected mice produce antibodies that cross-react with plant, insect, and mammalian glycoproteins and recognize the truncated biantennaryN-glycan Man3GlcNAc2-R.

To reveal the role of cross-reactive carbohydrate determinants in the host immune response in helminth infections and allergenicity, we developed monoclonal antibodies (mAbs) that recognize glycan epitopes present on glycoconjugates from both helminths and plants. An IgM mAb (100-4G11-A) was selected from a panel of anti-glycan mAbs generated from Schistosoma-infected or immunized mice because ...

متن کامل

Identification of Antigenic Glycans from Schistosoma mansoni by Using a Shotgun Egg Glycan Microarray.

Infection of mammals by the parasitic helminth Schistosoma mansoni induces antibodies to glycan antigens in worms and eggs, but the differential nature of the immune response among infected mammals is poorly understood. To better define these responses, we used a shotgun glycomics approach in which N-glycans from schistosome egg glycoproteins were prepared, derivatized, separated, and used to g...

متن کامل

Human Helminth Co-Infection: Analysis of Spatial Patterns and Risk Factors in a Brazilian Community

BACKGROUND Individuals living in areas endemic for helminths are commonly infected with multiple species. Despite increasing emphasis given to the potential health impacts of polyparasitism, few studies have investigated the relative importance of household and environmental factors on the risk of helminth co-infection. Here, we present an investigation of exposure-related risk factors as sourc...

متن کامل

Hybridoma-derived antibody with immunodiagnostic potential for schistosomiasis japonica.

A murine hybridoma-derived antibody (IPH.134) has been produced which has apparent high binding specificity for an extract of Schistosoma japonicum adult worms. No binding was detected to extracts of S. japonicum eggs or to extracts from other adult trematodes (Fasciola hepatica, Paragonimus westermanii, Clonorchis sinensis, and Schistosoma mansoni) and several other helminths and protozoa. Whe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2006